Supplements Information 2lossweight.com

Treatment of Heart Disease with Coenzyme Q10


Since its discovery in the late 1950â??s Coenzyme Q10 (CoQ10) has received much attention as a necessary compound for proper cellular function. It is the essential coenzyme necessary for the production of ATP (adenosine triphosphate) upon which all cellular functions depend. Without ATP our bodies cannot function properly. Without CoQ10, ATP cannot function. This connection has made CoQ10 a very important object of study in relation to chronic disease.

In many cases the presence of chronic disease is associated with inadequate levels of CoQ10. But no area of study has received more attention than the relation between CoQ10 and heart disease. That is because CoQ10 is believed to be of fundamental importance in cells with high metabolic demands such as cardiac cells. A further reason the connection of heart disease and CoQ10 has gained so much attention is because heart conditions of many kinds are associated with chronically low CoQ10 levels.

CoQ10 is highly concentrated in heart muscle cells because of their high energy requirements. Add this to the fact that heart disease is the number one killer in developed and developing countries and one can see why the bulk of scientific research on CoQ10 has been concerned with heart disease. Specifically, studies on congestive heart failure have demonstrated a strong correlation between the severity of heart failure and the degree of CoQ10 deficiency. The lower the levels of CoQ10 in the heart muscles the more severe the heart failure. If indeed CoQ10 deficiency is a primary cause of congestive heart failure then, in such cases, the remedy is simple and cost effective; CoQ10 supplementation.

Congestive heart failure is a condition where the heart does not pump effectively resulting in an accumulation of fluid in the lungs. Symptoms may include shortness of breath, difficulty breathing when lying flat and leg or ankle swelling. Causes include chronic hypertension, cardiomyopathy (primary heart disease) and myocardial infarction (irreversible injury to heart muscles). Heart muscle strength is measure by the ejection fraction which is a measure of the fraction of blood pumped out of the heart with each beat. A low ejection fraction indicates a weak heart.

Several trials have been conducted involving patients with enlarged weak heart muscles of unknown causes. For those of you who like difficult phrases this condition (or variety of conditions) is known as idiopathic dilated cardiomyopathy. In these trials CoQ10 supplementation was compared to placebo effects. Standard treatments for heart failure were not discontinued. The results were measured by echocardiography (a diagnostic test which uses ultrasound waves to make images of the heart chambers, valves and surrounding structures).

The overall results of CoQ10 supplementation demonstrated a steady and continued improvement in heart function as well as steady and continued reduction in patient symptoms including fatigue, chest pains, palpitations and breathing difficulty. Patients with more establish and long-term cases showed gradual improvement but did not gain normal heart function. Patients with newer cases of heart failure demonstrated much more rapid improvement often returning to normal heart function.

Papers numbering in the hundreds from eight different symposia have been written and presented on the effects of CoQ10 on heart disease. International clinical studies have also been conducted in the United States, Japan, Germany, Italy and Sweden. Together these studies and the papers that have been derived from them demonstrate significant improvement in heart muscle function while causing no adverse effects.

One particular area of study involves diastolic dysfunction which is one of the earliest signs of myocardial failure. Diastole is the phase of the cardiac cycle when the heart is filled with returning blood. Because this phase requires more cellular energy than the systolic phase (when the blood is pushed out of the heart) it is more dependent on CoQ10. Diastolic dysfunction is a stiffening of the heart muscle which naturally restricts the heartâ??s ability to pump. This condition is associated with many cardiac disorders. Hypertension is among these disorders. As the heart muscles become stiff there is often a corresponding rise in blood pressure. When the diastolic dysfunction is reversed, blood pressure tends to lower as well.

In one study involving 109 patients with hypertension, CoQ10 supplementation was added to normal hypertension treatments. In an average of 4.4 months 51% of the patients were able stop using at least one blood pressure lowering medication. Some were able to stop using up to three medications. Another study produced similar results. In that study 43% of 424 patients were able to stop using between one and three cardiovascular drugs because of CoQ10 supplementation.

These examples are just a drop in the bucket. Diastolic dysfunction (and by proxy, hypertension) includes only a small sampling of heart conditions that respond favorably to CoQ10 supplementation. Other areas of research show great promise for CoQ10 treatments. Among these are cancer and AIDS. But such conditions are beyond the scope of this essay. CoQ10 is essential to the proper functioning of all cell types. It is not surprising, therefore, to find a diverse number of diseases that respond favorably to CoQ10 supplementation. Since all metabolically active tissues are highly sensitive to CoQ10 deficiency, we can expect to see CoQ10 research expand to many other areas of chronic diseases.

Greg holds degrees in science, divinity and philosophy and is currently an I.T. developer.

http://www.optimal-heart-health.com/coq10.html


MORE RESOURCES:

McCain Letter Outlines Supplement Goal
Natural Products Industry Insider
Health, Education, Labor and Pensions Committee Chair Tom Harkin (D-IA), outlining key areas of common ground over dietary supplement legislation. ...
Hatch, McCain reach deal on dietary supplementsSalt Lake Tribune
Stricter oversight of dietary supplements closerBusinessWeek
Hatch, McCain reach agreement over Dietary Supplement Safety Act of 2010Drug Store News
WQAD -Bismarck Tribune -NewsWithViews.com
all 36 news articles »


PR Web (press release)

AARP Medicare Supplements: Lower Premiums Announced
Tucson Citizen
AARP/UnitedHealthcare has released rates in Arizona for its “Modernized Medicare Supplements” which take effect after June 1, 2010. ...
Medicare Supplement Plan N Information and Rates Now Available Through ...PR Web (press release)

all 3 news articles »


Phoenix officer reinstated in steroid case
Arizona Republic
Ramirez and police-union representatives said the department fails to educate officers about supplements containing steroid-like substances, urging a more ...

and more »


Super Supplements coming to downtown
Bizjournals.com
Super Supplements, a regional health supplement store, is leasing one of the most prominent empty spaces in downtown Portland. ...

and more »


WSAU

Board OKs supplement payments
2TheAdvocate
LUTCHER — The St. James Parish School District will pay the $5000 annual supplements the state promised teachers who achieve National Board ...
Local funds targetedOpelousas Daily World
Baldwin County school board members warned of more teacher cutsPress-Register - al.com (blog)

all 289 news articles »


Planet Diet – Presenting Comprehensive Information for Diet Supplement
BigNews.biz (press release)
Planet Diet (the well-known health and wellness portal) presents comprehensive coverage of all diet beneficial supplements for human body. ...



What Parents Should Know About Kids and Supplements
Medfinds
Can a nutritional supplement take the place of eating healthful whole foods? Nutrition research strongly suggests that the answer is no. ...

and more »


ABC News

Lawsuit claims PCBs found in 10 fish oil supplements; product...
San Jose Mercury News
SANTA CRUZ - People buying certain fish oil supplements to get the benefit of omega-3 fatty acids are ingesting chemicals banned in 1979, ...
Lawsuit says fish oil supplements contain PCBSan Francisco Chronicle
CORRECTED: Fish oil makers, drugstores, sued over supplementsReuters
Lawsuit Raises Fish Oil Supplement ConcernsABC News
ABC7Chicago.com -Avvo -Justice News Flash
all 200 news articles »



PR Web (press release)

Twinlab Launches New Resveratrol Supplement for Adults
Trading Markets (press release)
The innovative quick-dissolve DOT delivery allows for an absorption rate 25-times better than that of a traditional oral supplement capsule when used as ...
Twinlab Launches New Omega-3 Powder in Single-Serving Stick Packs for Busy ...PR Web (press release)

all 6 news articles »

Google News

home | site map
© 2006